Tag: proton pump inhibitors
Proton Pump Inhibitors and Antifungals: How They Interfere with Absorption and Effectiveness
Jan, 6 2026Proton pump inhibitors can block absorption of key antifungals like itraconazole and ketoconazole, reducing their effectiveness by up to 60%. Fluconazole isn’t affected by stomach pH, but it interacts with liver enzymes. New research shows PPIs may even boost antifungal power in resistant fungi.
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